CATH Domain 5d8uA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.91	Restriction Endonuclease
	3.40.91.90	Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain

Domain Context

CATH Clusters

Superfamily	Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

C3W5S0_I09A0

Influenza A virus (A/California/04/2009(H1N1))

Polymerase acidic protein

PDB Structure

PDB	5D8U
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Song, M.S., Kumar, G., Shadrick, W.R., Zhou, W., Jeevan, T., Li, Z., Slavish, P.J., Fabrizio, T.P., Yoon, S.W., Webb, T.R., Webby, R.J., White, S.W. Proc.Natl.Acad.Sci.USA