CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein-like

Enzyme Information

UniProtKB Entries (1)

Q8TCU6
PREX1_HUMAN
Homo sapiens
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

PDB Structure

PDB 5D27
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
Cash, J.N., Davis, E.M., Tesmer, J.J.
Structure
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