CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.1230 | Nucleotide cyclase |
Domain Context
CATH Clusters
| Superfamily | Nucleotide cyclase |
| Functional Family | Adenylate cyclase type 10 |
Enzyme Information
| 4.6.1.1 |
Adenylate cyclase.
based on mapping to UniProt Q96PN6
ATP = 3',5'-cyclic AMP + diphosphate.
-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.
|
UniProtKB Entries (1)
| Q96PN6 |
ADCYA_HUMAN
Homo sapiens
Adenylate cyclase type 10
|
PDB Structure
| PDB | 5D0R |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site.
J.Biol.Chem.
|
