CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.260 | Sortase; Chain: A; |
|
2.40.260.10 | Sortase |
Domain Context
CATH Clusters
| Superfamily | Sortase |
| Functional Family |
Enzyme Information
| 3.4.22.70 |
Sortase A.
based on mapping to UniProt Q9XA14
The enzyme catalyzes a cell wall sorting reaction in which a surface protein with a sorting signal containing a LPXTG motif is cleaved between the Thr and Gly residue. The resulting threonine carboxyl end of the protein is covalently attached to a pentaglycine cross-bridge of peptidoglycan.
-!- Belongs to peptidase family C60.
|
UniProtKB Entries (1)
| Q9XA14 |
SRTE1_STRCO
Streptomyces coelicolor A3(2)
Sortase SrtE1
|
PDB Structure
| PDB | 5CUW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the first class E sortase transpeptidase, SrtE1 from Streptomyces coelicolor
To be published
|