CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family |
Enzyme Information
| 3.4.24.35 |
Gelatinase B.
based on mapping to UniProt P14780
Cleavage of gelatin types I and V and collagen types IV and V.
-!- Belongs to peptidase family M10B.
|
UniProtKB Entries (1)
| P14780 |
MMP9_HUMAN
Homo sapiens
Matrix metalloproteinase-9
|
PDB Structure
| PDB | 5CUH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Discovery of a new selective inhibitor of A Disintegrin And Metalloprotease 10 (ADAM-10) able to reduce the shedding of NKG2D ligands in Hodgkin's lymphoma cell models.
Eur.J.Med.Chem.
|