CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.580 | Citrate Synthase; domain 1 | |
1.10.580.10 | Citrate Synthase, domain 1 |
Domain Context
CATH Clusters
Superfamily | Citrate Synthase, domain 1 |
Functional Family | Citrate synthase |
Enzyme Information
2.3.3.1 |
Citrate (Si)-synthase.
based on mapping to UniProt P23007
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
-!- The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, which is found in some anaerobes. -!- Citrate synthase for which the stereospecificity with respect to C(2) of oxaloacetate has not been established are included in EC 2.3.3.16. -!- Formerly EC 4.1.3.7.
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UniProtKB Entries (1)
P23007 |
CISY_CHICK
Gallus gallus
Citrate synthase, mitochondrial
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PDB Structure
PDB | 5CTS |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Proposed mechanism for the condensation reaction of citrate synthase: 1.9-A structure of the ternary complex with oxaloacetate and carboxymethyl coenzyme A.
Biochemistry
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