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CATH Classification

Domain Context

CATH Clusters

Superfamily alix/aip1 like domains
Functional Family Tyrosine-protein phosphatase non-receptor type 23

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q9H3S7
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

O75886
STAM2_HUMAN
Homo sapiens
Signal transducing adapter molecule 2

PDB Structure

PDB 5CRV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Study of the HD-PTP Bro1 Domain in a Complex with the Core Region of STAM2, a Subunit of ESCRT-0
Lee, J., Oh, K.-J., Lee, D., Kim, B.Y., Choi, J.S., Ku, B., Kim, S.J.
Plos One
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