CATH Domain 5cklA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.3290	Fic-like fold
	1.10.3290.10	Fido-like domain

Domain Context

CATH Clusters

Superfamily	Fido-like domain
Functional Family	Protein adenylyltransferase NmFic

Enzyme Information

2.7.7.n1

Protein adenylyltransferase.

based on mapping to UniProt Q7DDR9

(1) ATP + [protein]-L-tyrosine = diphosphate + [protein]-O(4)- (5'-adenylyl)-L-tyrosine. (2) ATP + [protein]-L-threonine = diphosphate + [protein]-O(4)- (5'-adenylyl)-L-threonine.

UniProtKB Entries (1)

Q7DDR9

NMFIC_NEIMB

Neisseria meningitidis MC58

Protein adenylyltransferase NmFic

PDB Structure

PDB	5CKL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Stanger, F.V., Burmann, B.M., Harms, A., Aragao, H., Mazur, A., Sharpe, T., Dehio, C., Hiller, S., Schirmer, T. Proc.Natl.Acad.Sci.USA