CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.30.140
Functional Family DNA (Cytosine-5)-methyltransferase 3B isoform 3

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt Q9UBC3
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

Q9UBC3
DNM3B_HUMAN
Homo sapiens
DNA (cytosine-5)-methyltransferase 3B

PDB Structure

PDB 5CIU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B.
Rondelet, G., Dal Maso, T., Willems, L., Wouters, J.
J.Struct.Biol.
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