CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10320 | LmbE-like |
Domain Context
CATH Clusters
| Superfamily | LmbE-like |
| Functional Family | 4-oxalmesaconate hydratase |
Enzyme Information
| 4.2.1.83 |
4-oxalmesaconate hydratase.
based on mapping to UniProt Q88JX8
2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E,3E)-4-hydroxybuta-1,3- diene-1,2,4-tricarboxylate + H(2)O.
-!- This enzyme participates in the degradation of protocatechuate (via the meta-cleavage pathway), syringate and gallate, catalyzing the reaction in the opposite direction. -!- It accepts the enol-form of 4-oxalomesaconate, 2-hydroxy-4-carboxy- hexa-2,4-dienedioate.
|
UniProtKB Entries (1)
| Q88JX8 |
GALB_PSEPK
Pseudomonas putida KT2440
4-oxalmesaconate hydratase
|
PDB Structure
| PDB | 5CGZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and Kinetic Characterization of the 4-Carboxy-2-hydroxymuconate Hydratase from the Gallate and Protocatechuate 4,5-Cleavage Pathways of Pseudomonas putida KT2440.
J.Biol.Chem.
|