CATH Domain 5cgvA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.91	Restriction Endonuclease
	3.40.91.90	Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain

Domain Context

CATH Clusters

Superfamily	Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

C3W5S0_I09A0

Influenza A virus (A/California/04/2009(H1N1))

Polymerase acidic protein

PDB Structure

PDB	5CGV
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Song, M.S., Kumar, G., Shadrick, W.R., Zhou, W., Jeevan, T., Li, Z., Slavish, P.J., Fabrizio, T.P., Yoon, S.W., Webb, T.R., Webby, R.J., White, S.W. Proc. Natl. Acad. Sci. U.S.A.