CATH Domain 5cgaA00

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1190	UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase
	3.40.1190.20	Ribokinase

Superfamily	3.40.1190.20
Functional Family

2.7.1.50

Hydroxyethylthiazole kinase.

based on mapping to UniProt Q6GEY3

ATP + 4-methyl-5-(2-hydroxyethyl)thiazole = ADP + 4-methyl-5- (2-phosphonooxyethyl)thiazole.

THIM_STAAR

Staphylococcus aureus subsp. aureus MRSA252

Hydroxyethylthiazole kinase

PDB	5CGA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections. Drebes, J., Kunz, M., Windshugel, B., Kikhney, A.G., Muller, I.B., Eberle, R.J., Oberthur, D., Cang, H., Svergun, D.I., Perbandt, M., Betzel, C., Wrenger, C. Sci Rep