CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.360 | Dihydrodipicolinate Reductase; domain 2 |
|
3.30.360.10 | Dihydrodipicolinate Reductase; domain 2 |
Domain Context
CATH Clusters
| Superfamily | Dihydrodipicolinate Reductase; domain 2 |
| Functional Family | Glyceraldehyde-3-phosphate dehydrogenase |
Enzyme Information
| 1.2.1.12 |
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
based on mapping to UniProt Q64467
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
-!- Also acts very slowly on D-glyceraldehyde and some other aldehydes. -!- Thiols can replace phosphate.
|
UniProtKB Entries (1)
| Q64467 |
G3PT_MOUSE
Mus musculus
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
|
PDB Structure
| PDB | 5C7I |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.
Mol. Hum. Reprod.
|
