CATH Domain 5c1xA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Genome polyprotein

Enzyme Information

UniProtKB Entries (1)

A9XG43_9ENTO

Enterovirus A71

Genome polyprotein

PDB Structure

PDB	5C1X
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71 Zhang, L., Huang, G., Cai, Q., Zhao, C., Tang, L., Ren, H., Li, P., Li, N., Huang, J., Chen, X., Guan, Y., You, H., Chen, S., Li, J., Lin, T. J.Mol.Recognit.