CATH Classification

Domain Context

CATH Clusters

Superfamily MHC class I-like antigen recognition-like
Functional Family H-2 class I histocompatibility antigen, alpha chain

Enzyme Information

UniProtKB Entries (1)

P01308
INS_HUMAN
Homo sapiens
Insulin

PDB Structure

PDB 5C0D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Cole, D.K., Bulek, A.M., Dolton, G., Schauenberg, A.J., Szomolay, B., Rittase, W., Trimby, A., Jothikumar, P., Fuller, A., Skowera, A., Rossjohn, J., Zhu, C., Miles, J.J., Peakman, M., Wooldridge, L., Rizkallah, P.J., Sewell, A.K.
J.Clin.Invest.