CATH Domain 5bnjB02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.472	Cyclin A; domain 1
	1.10.472.10	Cyclin-like

Domain Context

CATH Clusters

Superfamily	Cyclin-like
Functional Family	Putative cyclin-c

Enzyme Information

UniProtKB Entries (1)

CDK8_HUMAN

Homo sapiens

Cyclin-dependent kinase 8

PDB Structure

PDB	5BNJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease. Dale, T., Clarke, P.A., Esdar, C., Waalboer, D., Adeniji-Popoola, O., Ortiz-Ruiz, M.J., Mallinger, A., Samant, R.S., Czodrowski, P., Musil, D., Schwarz, D., Schneider, K., Stubbs, M., Ewan, K., Fraser, E., TePoele, R., Court, W., Box, G., Valenti, M., de Haven Brandon, A., Gowan, S., Rohdich, F., Raynaud, F., Schneider, R., Poeschke, O., Blaukat, A., Workman, P., Schiemann, K., Eccles, S.A., Wienke, D., Blagg, J. Nat.Chem.Biol.