CATH Domain 5ayfA02

Superfamily	SET domain
Functional Family	Histone-lysine N-methyltransferase SETD7

2.1.1.43

Histone-lysine N-methyltransferase.

based on mapping to UniProt Q8WTS6

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

SETD7_HUMAN

Homo sapiens

Histone-lysine N-methyltransferase SETD7

PDB	5AYF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription Takemoto, Y., Ito, A., Niwa, H., Okamura, M., Fujiwara, T., Hirano, T., Handa, N., Umehara, T., Sonoda, T., Ogawa, K., Tariq, M., Nishino, N., Dan, S., Kagechika, H., Yamori, T., Yokoyama, S., Yoshida, M. J.Med.Chem.