CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.565 | Retinoid X Receptor |
|
1.10.565.10 | Retinoid X Receptor |
Domain Context
CATH Clusters
| Superfamily | Retinoid X Receptor |
| Functional Family | Oxysterols receptor LXR-alpha isoform 1 |
Enzyme Information
UniProtKB Entries (1)
| Q15788 |
NCOA1_HUMAN
Homo sapiens
Nuclear receptor coactivator 1
|
PDB Structure
| PDB | 5AVI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Discovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonists
Bioorg.Med.Chem.Lett.
|
