CATH Classification
Level | CATH Code | Description |
---|---|---|
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1 | Mainly Alpha |
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1.10 | Orthogonal Bundle |
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1.10.510 | Transferase(Phosphotransferase); domain 1 |
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1.10.510.10 | Transferase(Phosphotransferase) domain 1 |
Domain Context
CATH Clusters
Superfamily | Transferase(Phosphotransferase) domain 1 |
Functional Family | Dual specificity protein kinase TTK |
Enzyme Information
2.7.12.1 |
Dual-specificity kinase.
based on mapping to UniProt P33981
ATP + a protein = ADP + a phosphoprotein.
-!- This family of enzymes can phosphorylate both Ser/Thr and Tyr residues. -!- Formerly EC 2.7.1.37.
|
UniProtKB Entries (1)
P33981 |
TTK_HUMAN
Homo sapiens
Dual specificity protein kinase TTK
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PDB Structure
PDB | 5AP7 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Naturally Occurring Mutations in the Mps1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance.
Cancer Res.
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