CATH Domain 5ajpA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.550	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
	3.90.550.10	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family	Polypeptide N-acetylgalactosaminyltransferase

Enzyme Information

2.4.1.41

Polypeptide N-acetylgalactosaminyltransferase.

based on mapping to UniProt Q10471

(1) UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-serine. (2) UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine.

-!- The glycosyl residue is transferred to threonine or serine hydroxy groups on the polypeptide core of submaxillary mucin, kappa-casein, apofetuin and some other acceptors of high molecular mass.

UniProtKB Entries (1)

Q10471

GALT2_HUMAN

Homo sapiens

Polypeptide N-acetylgalactosaminyltransferase 2

PDB Structure

PDB	5AJP
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Dynamic Interplay between Catalytic and Lectin Domains of Galnac-Transferases Modulates Protein O-Glycosylation. Lira-Navarrete, E., De Las Rivas, M., Companon, I., Pallares, M.C., Kong, Y., Iglesias-Fernandez, J., Bernardes, G.J.L., Peregrina, J.M., Rovira, C., Bernado, P., Bruscolini, P., Clausen, H., Lostao, A., Corzana, F., Hurtado-Guerrero, R. Nat.Commun.