1 keywords

CATH Domain 5afhC00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.70 Distorted Sandwich
Topology 2.70.170 Acetylcholine Binding Protein; Chain: A,
Homologous Superfamily 2.70.170.10 Neurotransmitter-gated ion-channel ligand-binding domain

Domain Context

CATH Clusters

Superfamily Neurotransmitter-gated ion-channel ligand-binding domain
Functional Family

Enzyme Information

UniProtKB Entries (2)

P36544
ACHA7_HUMAN
Homo sapiens
Neuronal acetylcholine receptor subunit alpha-7
P58154
ACHP_LYMST
Lymnaea stagnalis
Acetylcholine-binding protein

PDB Structure

PDB 5AFH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular Blueprint of Allosteric Binding Sites in a Homologue of the Agonist-Binding Domain of the Alpha7 Nicotinic Acetylcholine Receptor.
Spurny, R., Debaveye, S., Farinha, A., Veys, K., Vos, A.M., Gossas, T., Atack, J., Bertrand, S., Bertrand, D., Danielson, U.H., Tresadern, G., Ulens, C.
Proc.Natl.Acad.Sci.USA