CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.10 | Roll | |
3.10.450 | Nuclear Transport Factor 2; Chain: A, | |
3.10.450.50 |
Domain Context
CATH Clusters
Superfamily | 3.10.450.50 |
Functional Family |
Enzyme Information
1.14.12.18 |
Biphenyl 2,3-dioxygenase.
based on mapping to UniProt P37334
Biphenyl + NADH + O(2) = (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+).
-!- The enzyme from Burkholderia fungorum strain LB400 (previously Pseudomonas sp.) is part of a multicomponent system composed of an NADH:ferredoxin oxidoreductase (FAD cofactor), a [2Fe-2S] Rieske-type ferredoxin, and a terminal oxygenase that contains a [2Fe-2S] Rieske- type iron-sulfur cluster and a catalytic mononuclear nonheme iron center. -!- Chlorine-substituted biphenyls can also act as substrates. -!- Similar to the three-component enzyme systems EC 1.14.12.3 and EC 1.14.12.11.
|
UniProtKB Entries (1)
P37333 |
BPHA_PARXL
Paraburkholderia xenovorans LB400
Biphenyl dioxygenase subunit alpha
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PDB Structure
PDB | 5AEW |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural Basis of the Enhanced Pollutant-Degrading Capabilities of an Engineered Biphenyl Dioxygenase.
J.Bacteriol.
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