CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.45 | Vanillyl-alcohol Oxidase; Chain A, domain 4 |
|
1.10.45.10 | Vanillyl-alcohol Oxidase; Chain A, domain 4 |
Domain Context
CATH Clusters
| Superfamily | Vanillyl-alcohol Oxidase; Chain A, domain 4 |
| Functional Family | Alkylglycerone-phosphate synthase |
Enzyme Information
| 2.5.1.26 |
Alkylglycerone-phosphate synthase.
based on mapping to UniProt P97275
1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion.
-!- The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.
|
UniProtKB Entries (1)
| P97275 |
ADAS_CAVPO
Cavia porcellus
Alkyldihydroxyacetonephosphate synthase, peroxisomal
|
PDB Structure
| PDB | 5AE3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Discovery of Inhibitors for the Ether Lipid-Generating Enzyme Agps as Anti-Cancer Agents.
Acs Chem.Biol.
|
