CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.300 | GMP Synthetase; Chain A, domain 3 |
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3.30.300.330 |
Domain Context
CATH Clusters
Superfamily | 3.30.300.330 |
Functional Family | Alkylglycerone-phosphate synthase |
Enzyme Information
2.5.1.26 |
Alkylglycerone-phosphate synthase.
based on mapping to UniProt P97275
1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion.
-!- The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.
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UniProtKB Entries (1)
P97275 |
ADAS_CAVPO
Cavia porcellus
Alkyldihydroxyacetonephosphate synthase, peroxisomal
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PDB Structure
PDB | 5AE3 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Discovery of Inhibitors for the Ether Lipid-Generating Enzyme Agps as Anti-Cancer Agents.
Acs Chem.Biol.
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