CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.499 | Aconitase; domain 3 | |
3.30.499.10 | Aconitase, domain 3 |
Domain Context
CATH Clusters
Superfamily | Aconitase, domain 3 |
Functional Family | Aconitate hydratase, mitochondrial |
Enzyme Information
4.2.1.3 |
Aconitate hydratase.
based on mapping to UniProt P16276
Citrate = isocitrate.
-!- Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate. -!- The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate. -!- Cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate. -!- Formerly EC 4.2.1.4.
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UniProtKB Entries (1)
P16276 |
ACON_PIG
Sus scrofa
Aconitate hydratase, mitochondrial
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PDB Structure
PDB | 5ACN |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure of activated aconitase: formation of the [4Fe-4S] cluster in the crystal.
Proc.Natl.Acad.Sci.USA
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