CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.418 | Actin-binding Protein, T-fimbrin; domain 1 |
|
1.10.418.10 | Calponin-like domain |
Domain Context
CATH Clusters
| Superfamily | Calponin-like domain |
| Functional Family | Alpha-actinin, sarcomeric |
Enzyme Information
UniProtKB Entries (1)
| P35609 |
ACTN2_HUMAN
Homo sapiens
Alpha-actinin-2
|
PDB Structure
| PDB | 5A38 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation.
Biochem.J.
|