CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.220 | Leucine Aminopeptidase, subunit E; domain 1 |
|
3.40.220.10 | Leucine Aminopeptidase, subunit E, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Leucine Aminopeptidase, subunit E, domain 1 |
| Functional Family | M17 leucyl aminopeptidase |
Enzyme Information
UniProtKB Entries (1)
| A0A024V0B1 |
A0A024V0B1_PLAFA
Plasmodium falciparum Vietnam Oak-Knoll (FVO)
Uncharacterized protein
|
PDB Structure
| PDB | 4ZYQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem.
|