CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.390 | Neutral Protease; domain 2 |
|
1.10.390.10 | Neutral Protease Domain 2 |
Domain Context
CATH Clusters
| Superfamily | Neutral Protease Domain 2 |
| Functional Family |
Enzyme Information
| 3.4.11.- |
Aminopeptidases.
based on mapping to UniProt O96935
|
UniProtKB Entries (1)
| O96935 |
AMP1_PLAFQ
Plasmodium falciparum FcB1/Columbia
M1 family aminopeptidase
|
PDB Structure
| PDB | 4ZX6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem.
|
