CATH Domain 4zx6A01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1730	tricorn interacting facor f3 domain

Domain Context

CATH Clusters

Superfamily	tricorn interacting facor f3 domain
Functional Family

Enzyme Information

3.4.11.-

Aminopeptidases.

based on mapping to UniProt O96935

UniProtKB Entries (1)

AMP1_PLAFQ

Plasmodium falciparum FcB1/Columbia

M1 family aminopeptidase

PDB Structure

PDB	4ZX6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Drinkwater, N., Vinh, N.B., Mistry, S.N., Bamert, R.S., Ruggeri, C., Holleran, J.P., Loganathan, S., Paiardini, A., Charman, S.A., Powell, A.K., Avery, V.M., McGowan, S., Scammells, P.J. Eur.J.Med.Chem.