CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.25 | Alpha Horseshoe | |
1.25.50 | Zincin-like fold | |
1.25.50.10 | Peptidase M1, alanyl aminopeptidase, C-terminal domain |
Domain Context
CATH Clusters
Superfamily | Peptidase M1, alanyl aminopeptidase, C-terminal domain |
Functional Family | M1 family aminopeptidase |
Enzyme Information
3.4.11.- |
Aminopeptidases.
based on mapping to UniProt O96935
|
UniProtKB Entries (1)
O96935 |
AMP1_PLAFQ
Plasmodium falciparum FcB1/Columbia
M1 family aminopeptidase
|
PDB Structure
PDB | 4ZW5 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem.
|