CATH Classification

Domain Context

CATH Clusters

Superfamily 2.170.220.10
Functional Family Methionine--tRNA ligase

Enzyme Information

UniProtKB Entries (1)

Q38C91
Q38C91_TRYB2
Trypanosoma brucei brucei TREU927
Methionyl-tRNA synthetase, putative

PDB Structure

PDB 4ZT3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors.
Zhang, Z., Koh, C.Y., Ranade, R.M., Shibata, S., Gillespie, J.R., Hulverson, M.A., Huang, W., Nguyen, J., Pendem, N., Gelb, M.H., Verlinde, C.L., Hol, W.G., Buckner, F.S., Fan, E.
Acs Infect Dis.