CATH Domain 4zrjA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.20	Ubiquitin-like (UB roll)
	3.10.20.90	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family	Merlin isoform 2

Enzyme Information

UniProtKB Entries (1)

MERL_HUMAN

Homo sapiens

Merlin

PDB Structure

PDB	4ZRJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Li, Y., Zhou, H., Li, F., Chan, S.W., Lin, Z., Wei, Z., Yang, Z., Guo, F., Lim, C.J., Xing, W., Shen, Y., Hong, W., Long, J., Zhang, M. Cell Res.