CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1310.20
Functional Family

Enzyme Information

3.6.4.12
DNA helicase.
based on mapping to UniProt P03132
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).

UniProtKB Entries (1)

P03132
REP68_AAV2S
Adeno-associated virus 2 Srivastava/1982
Protein Rep68

PDB Structure

PDB 4ZQ9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Insights into the Assembly of the Adeno-associated Virus Type 2 Rep68 Protein on the Integration Site AAVS1.
Musayev, F.N., Zarate-Perez, F., Bishop, C., Burgner, J.W., Escalante, C.R.
J.Biol.Chem.
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