CATH Domain 4zcwA02

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.120	Enolase-like C-terminal domain

Superfamily	Enolase-like C-terminal domain
Functional Family	Enolase 1

4.2.1.11

Phosphopyruvate hydratase.

based on mapping to UniProt P09104

2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O.

-!- Also acts on 3-phospho-D-erythronate.

ENOG_HUMAN

Homo sapiens

Gamma-enolase

PDB	4ZCW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	SF2312 is a natural phosphonate inhibitor of enolase. Leonard, P.G., Satani, N., Maxwell, D., Lin, Y.H., Hammoudi, N., Peng, Z., Pisaneschi, F., Link, T.M., Lee, G.R., Sun, D., Prasad, B.A., Di Francesco, M.E., Czako, B., Asara, J.M., Wang, Y.A., Bornmann, W., DePinho, R.A., Muller, F.L. Nat.Chem.Biol.