CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.5.4570
Functional Family

Enzyme Information

4.1.1.102
Phenacrylate decarboxylase.
based on mapping to UniProt B9WJ66
(1) 4-coumarate = 4-vinylphenol + CO(2). (2) Trans-cinnamate = styrene + CO(2). (3) Ferulate = 4-vinylguaiacol + CO(2).
-!- The enzyme, found in fungi, catalyzes the decarboxylation of phenacrylic acids present in plant cell walls. -!- It requires a prenylated flavin cofactor that is produced by EC 2.5.1.129.

UniProtKB Entries (1)

B9WJ66
FDC1_CANDC
Candida dubliniensis CD36
Ferulic acid decarboxylase 1

PDB Structure

PDB 4ZAD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
New cofactor supports alpha , beta-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition.
Payne, K.A., White, M.D., Fisher, K., Khara, B., Bailey, S.S., Parker, D., Rattray, N.J., Trivedi, D.K., Goodacre, R., Beveridge, R., Barran, P., Rigby, S.E., Scrutton, N.S., Hay, S., Leys, D.
Nature
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