CATH Classification
Level | CATH Code | Description |
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2 | Mainly Beta |
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2.10 | Ribbon |
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2.10.10 | Seminal Fluid Protein PDC-109 (Domain B) |
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2.10.10.20 | Carbohydrate-binding module superfamily 5/12 |
Domain Context
CATH Clusters
Superfamily | Carbohydrate-binding module superfamily 5/12 |
Functional Family |
Enzyme Information
3.2.1.14 |
Chitinase.
based on mapping to UniProt P11797
Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta- linkages in chitin and chitodextrins.
-!- The enzyme binds to chitin and randomly cleaves glycosidic linkages in chitin and chitodextrins in a non-processive mode, generating chitooligosaccharides and free ends on which exo-chitinases and exo- chitodextrinases can act. -!- Activity is greatly stimulated in the presence of EC 1.14.99.53, which attacks the crystalline structure of chitin and makes the polymer more accesible to the chitinase. -!- Cf. EC 3.2.1.202.
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UniProtKB Entries (1)
P11797 |
CHIB_SERMA
Serratia marcescens
Chitinase B
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PDB Structure
PDB | 4Z2L |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
J.Med.Chem.
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