CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family |
Enzyme Information
| 2.5.1.55 |
3-deoxy-8-phosphooctulonate synthase.
based on mapping to UniProt P56060
Phosphoenolpyruvate + D-arabinose 5-phosphate + H(2)O = 3-deoxy-D-manno- octulosonate 8-phosphate + phosphate.
-!- Formerly EC 4.1.2.16.
|
UniProtKB Entries (1)
| P56060 |
KDSA_HELPY
Helicobacter pylori 26695
2-dehydro-3-deoxyphosphooctonate aldolase
|
PDB Structure
| PDB | 4Z1B |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS).
Eur.J.Med.Chem.
|
