CATH Classification

Domain Context

CATH Clusters

Superfamily Haem peroxidase domain superfamily, animal type
Functional Family Prostaglandin G/H synthase 2

Enzyme Information

1.14.99.1
Prostaglandin-endoperoxide synthase.
based on mapping to UniProt Q05769
Arachidonate + AH(2) + 2 O(2) = prostaglandin H(2) + A + H(2)O.
-!- Acts both as a dioxygenase and as a peroxidase.

UniProtKB Entries (1)

Q05769
PGH2_MOUSE
Mus musculus
Prostaglandin G/H synthase 2

PDB Structure

PDB 4Z0L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2.
Neumann, W., Xu, S., Sarosi, M.B., Scholz, M.S., Crews, B.C., Ghebreselasie, K., Banerjee, S., Marnett, L.J., Hey-Hawkins, E.
Chemmedchem
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