CATH Domain 4yofA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.450	Beta-Lactamase
	3.30.450.40	GAF domain

Domain Context

CATH Clusters

Superfamily	3.30.450.40
Functional Family	Oxygen sensor histidine kinase response regulator DevS/DosS

Enzyme Information

2.7.13.3

Histidine kinase.

based on mapping to UniProt P9WGK2

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.

UniProtKB Entries (1)

P9WGK2

DEVS_MYCTO

Mycobacterium tuberculosis CDC1551

Oxygen sensor histidine kinase response regulator DevS/DosS

PDB Structure

PDB	4YOF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography. Basudhar, D., Madrona, Y., Kandel, S., Lampe, J.N., Nishida, C.R., de Montellano, P.R. J.Biol.Chem.