CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1580 | Nucleoside phosphorylase domain |
Domain Context
CATH Clusters
| Superfamily | Nucleoside phosphorylase domain |
| Functional Family | MTA/SAH nucleosidase family protein |
Enzyme Information
| 3.2.2.9 |
Adenosylhomocysteine nucleosidase.
based on mapping to UniProt P0AF12
S-adenosyl-L-homocysteine + H(2)O = S-(5-deoxy-D-ribos-5-yl)-L- homocysteine + adenine.
|
UniProtKB Entries (1)
| P0AF12 |
MTNN_ECOLI
Escherichia coli K-12
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
|
PDB Structure
| PDB | 4YML |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Tight binding enantiomers of pre-clinical drug candidates.
Bioorg.Med.Chem.
|