CATH Domain 4yi7A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1030	Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2
	3.40.1030.10	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain

Domain Context

CATH Clusters

Superfamily	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
Functional Family	Anthranilate phosphoribosyltransferase

Enzyme Information

2.4.2.18

Anthranilate phosphoribosyltransferase.

based on mapping to UniProt P00500

N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate.

-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).

UniProtKB Entries (1)

P00500

TRPD_ACIAD

Acinetobacter baylyi ADP1

Anthranilate phosphoribosyltransferase

PDB Structure

PDB	4YI7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Substrate inhibition of protein in tryptophan biosynthesis pathway redirects flux to aromatic catabolism in Acinetobacter baylyi ADP1. Evans, G.E., Nigon, L.V., Ponniah, K., Burr, N., Anderson, B.F., Norris, G.E., Patrick, W.M. To Be Published