CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.601 | RNA Polymerase Primary Sigma Factor |
|
1.10.601.10 | RNA Polymerase Primary Sigma Factor |
Domain Context
CATH Clusters
| Superfamily | RNA Polymerase Primary Sigma Factor |
| Functional Family | RNA polymerase sigma factor RpoD |
Enzyme Information
UniProtKB Entries (2)
| P00579 |
RPOD_ECOLI
Escherichia coli K-12
RNA polymerase sigma factor RpoD
|
| A7ZSI4 |
RPOA_ECO24
Escherichia coli O139:H28 str. E24377A
DNA-directed RNA polymerase subunit alpha
|
PDB Structure
| PDB | 4YFX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein.
J.Med.Chem.
|
