CATH Classification
Level | CATH Code | Description |
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1 | Mainly Alpha |
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1.10 | Orthogonal Bundle |
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1.10.150 | DNA polymerase; domain 1 |
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1.10.150.110 | DNA polymerase beta, N-terminal domain-like |
Domain Context
CATH Clusters
Superfamily | DNA polymerase beta, N-terminal domain-like |
Functional Family | DNA polymerase mu |
Enzyme Information
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt Q9NP87
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
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UniProtKB Entries (1)
Q9NP87 |
DPOLM_HUMAN
Homo sapiens
DNA-directed DNA/RNA polymerase mu
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PDB Structure
PDB | 4YD1 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Creative template-dependent synthesis by human polymerase mu.
Proc.Natl.Acad.Sci.USA
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