CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.620 | q2cbj1_9rhob like domain |
Domain Context
CATH Clusters
| Superfamily | q2cbj1_9rhob like domain |
| Functional Family | Verruculogen synthase |
Enzyme Information
| 1.14.11.38 |
Verruculogen synthase.
based on mapping to UniProt Q4WAW9
Fumitremorgin B + 2-oxoglutarate + 2 O(2) + AH(2) = verruculogen + succinate + CO(2) + H(2)O + A.
-!- Found in the fungus Aspergillus fumigatus. -!- Both atoms of a dioxygen molecule are incorporated into verruculogen. -!- Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgin A.
|
UniProtKB Entries (1)
| Q4WAW9 |
FTMF_ASPFU
Aspergillus fumigatus Af293
Verruculogen synthase
|
PDB Structure
| PDB | 4Y5S |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Endoperoxide formation by an alpha-ketoglutarate-dependent mononuclear non-haem iron enzyme.
Nature
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