CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.39 | Alpha-1-antitrypsin; domain 1 |
|
2.30.39.10 | Alpha-1-antitrypsin, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Alpha-1-antitrypsin, domain 1 |
| Functional Family | alpha-1-antitrypsin isoform X1 |
Enzyme Information
UniProtKB Entries (1)
| Q8IW75 |
SPA12_HUMAN
Homo sapiens
Serpin A12
|
PDB Structure
| PDB | 4Y40 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A unique serpin P1' glutamate and a conserved beta-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin).
Biochem.J.
|
