CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.497 | Antithrombin; Chain I, domain 2 |
|
3.30.497.10 | Antithrombin, subunit I, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Antithrombin, subunit I, domain 2 |
| Functional Family | Serine protease inhibitor |
Enzyme Information
UniProtKB Entries (1)
| Q8IW75 |
SPA12_HUMAN
Homo sapiens
Serpin A12
|
PDB Structure
| PDB | 4Y40 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A unique serpin P1' glutamate and a conserved beta-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin).
Biochem.J.
|
