CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.240 | CRO Repressor |
|
3.30.240.40 | E6 early regulatory protein |
Domain Context
CATH Clusters
| Superfamily | E6 early regulatory protein |
| Functional Family | Protein E6 |
Enzyme Information
UniProtKB Entries (3)
| P0AEX9 |
MALE_ECOLI
Escherichia coli K-12
Maltose/maltodextrin-binding periplasmic protein
|
| Q05086 |
UBE3A_HUMAN
Homo sapiens
Ubiquitin-protein ligase E3A
|
| P03126 |
VE6_HPV16
Human papillomavirus type 16
Protein E6
|
PDB Structure
| PDB | 4XR8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.
Nature
|
