CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.70 | Cathepsin B; Chain A |
|
3.90.70.10 | Cysteine proteinases |
Domain Context
CATH Clusters
| Superfamily | Cysteine proteinases |
| Functional Family | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 |
Enzyme Information
| 3.1.13.4 |
Poly(A)-specific ribonuclease.
based on mapping to UniProt P53010
Exonucleolytic cleavage of poly(A) to 5'-AMP.
-!- Cleaves poly(A) in either the single- or double-stranded form.
|
UniProtKB Entries (1)
| P53010 |
PAN2_YEAST
Saccharomyces cerevisiae S288C
PAN2-PAN3 deadenylation complex catalytic subunit PAN2
|
PDB Structure
| PDB | 4XR7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Nat. Struct. Mol. Biol.
|
