CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.460 | Beta Polymerase; domain 2 |
|
3.30.460.10 | Beta Polymerase, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Beta Polymerase, domain 2 |
| Functional Family | 2'-5'-oligoadenylate synthetase 1 |
Enzyme Information
UniProtKB Entries (1)
| Q15646 |
OASL_HUMAN
Homo sapiens
2'-5'-oligoadenylate synthase-like protein
|
PDB Structure
| PDB | 4XQ7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling.
Nucleic Acids Res.
|
