CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.30 | Elongation Factor Tu (Ef-tu); domain 3 |
|
2.40.30.40 | Peptidase M42, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Peptidase M42, domain 2 |
| Functional Family |
Enzyme Information
| 3.4.11.15 |
Aminopeptidase Y.
based on mapping to UniProt Q8TZW4
Preferentially, release of N-terminal lysine.
-!- Inhibited by Zn(2+) and Mn(2+). -!- Hydrolyzes L-lysyl-4-nitroanilide and, more slowly, L-arginyl-4- nitroanilide. -!- Belongs to peptidase family M28B.
|
UniProtKB Entries (1)
| Q8TZW4 |
AMPK_PYRFU
Pyrococcus furiosus DSM 3638
Lysyl aminopeptidase
|
PDB Structure
| PDB | 4X8I |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Tuned by metals: the TET peptidase activity is controlled by 3 metal binding sites.
Sci Rep
|